Beilstein J. Nanotechnol.2021,12, 1339–1364, doi:10.3762/bjnano.12.99
combating MDR in cancer cells.
Functionalized MFe2O4 NPs showed higher IC50 in normal cells as compared to cancer cells
The cytotoxicity of drug-loaded NPs was assessed in fresh humanlymphocytes to determine their biocompatibility in vitro using the MTT assay. Freshly collected lymphocytes were exposed to
PDF
Figure 1: (a) Rietveld-refined XRD pattern of MFe2O4 (M = Fe, Co, Ni, Zn) NPs with SAED images showing differ...
Beilstein J. Nanotechnol.2017,8, 1494–1501, doi:10.3762/bjnano.8.149
lymphocytes and reduces the fraction of necrotic cells.
Keywords: atomic force microscopy; C60 fullerene; cisplatin; comet assay; computer simulation; dynamic light scattering; flow cytometry; humanlymphocytes; toxicity in vitro; Introduction
The water-soluble inorganic bi-valent platinum derivative
correlation between the genotoxic response and the concentration of an aqueous suspension of nC60 (178 nm in size) was observed at 2.2 µg/L in humanlymphocytes using a single-cell gel electrophoresis assay [27]. In contrast, with stable C60 fullerene suspensions in 0.1% carboxymethylcellulose sodium or 0.1
. The results clearly demonstrate that water-soluble C60 fullerene nanoparticles (0.1 mg/mL) do not induce DNA strand breaks in normal and transformed cells. C60 fullerene in the mixture with Cis does not influence genotoxic Cis activity in vitro, affects the cell-death mode in treated resting human
PDF
Figure 1:
DLS (hydrodynamic size) results of C60FAS (grey; concentration 0.15 mg/mL) and C60+Cis mixture (red...